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1 Department of Oral Pathology and Periodontology, Tufts College Dental School, Boston, Mass.
The alarm reaction of the general adaptation syndrome was produced in albino rats by using repeated injections of 4 per cent formaldehyde as the stressor mechanism. The presence of the alarm reaction was demonstrated by gross and microscopic changes in the adrenal glands, thymus, spleen, and gastrointestinal tract. No notable gross or microscopic changes were observed in the periodontal tissues. Degenerative changes in the salivary glands were noted in the alarm reaction.
Submitted on February 27, 1953
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