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J Dent Res 32(4): 469-485, 1953
© 1953 International and American Associations for Dental Research
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EFFECT OF CERTAIN CONCENTRATIONS OF FLUORIDE ON ENAMEL AND DENTIN AS FORMED IN TRANSPLANTS OF TOOTH GERMS AND RELATED STUDIES

HAROLD S. FLEMING D.M.D., M.SC., D.SC.1

1 Department of Pathology, Yale University School of Medicine, New Haven, Conn.

1. Calcification of enamel and dentin was retarded in the presence of fluorides.

2. The structure of the ameloblasts was altered.

3. In the presence of methylcholanthrene and fluorides no keratinized cells of tooth germ epithelium were formed.

4. Dentin formed in transplants did not revise itself into osteoid tissue over long periods.

5. Cartilage frequently was found in association with dentin.

6. Action of the fluoride ion seemed at the enzyme level.

Submitted on October 27, 1952






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