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J Dent Res 31(6): 812-814, 1952
© 1952 International and American Associations for Dental Research
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THE REPARATIVE EFFECT OF ANTABUSE (TETRAETHYLTHIURAM DISULFIDE) UPON DENTAL CHANGES IN VITAMIN E DEFICIENT RATS

J. J. PINDBORG 1

1 Departments of Dental Histology, University of Illinois and the Royal Dental College, Denmark and Medicinalco, Ltd., Copenhagen

The present study is based on the anatomic and histologic examination of 20 rats. One-month-old rats were kept on a vitamin E deficient diet for a period of 3 months. Ten of the rats then received 0.025 per cent Antabuse in addition to the experimental diet for a period of 4 months, while the other 10 were continued on the experimental diet alone.

The rats receiving the vitamin E deficient diet showed lack of pigmentation and typical histologic changes in the enamel organ. Rats receiving Antabuse added to vitamin E deficient diet did not show any changes in the incisors.

Submitted on June 14, 1952






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