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J Dent Res 31(1): 129-131, 1952
© 1952 International and American Associations for Dental Research
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STUDIES ON THE EFFECT OF METALLIC SALTS ON ACID PRODUCTION IN SALIVA. I

J. C. FORBES 1 and J. D. SMITH 1

1 Departments of Biochemistry and Chemistry, Medical College of Virginia, Richmond, Va.

The effect of various metallic salts upon acid production in saliva containing sucrose has been studied. Copper, nickel, gold, silver, and mercury salts exerted the greatest inhibitory action on acid production. Magnesium, cobalt, manganese, aluminum, iron, and chromic salts showed little or no activity. Copper at a concentration of 0.25 mg. per 100 ml. of saliva containing sucrose definitely inhibited acid formation while a concentration of 3 to 4 mg. per 100 ml. of saliva caused complete inhibition of acid production.

Submitted on June 13, 1951






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