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J Dent Res 30(3): 337-345, 1951
© 1951 International and American Associations for Dental Research

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CHANGES IN THE MANDIBULAR JOINT AND PERIODONTIUM OF VITAMIN B COMPLEX DEFICIENT RATS AND THE COURSE OF REPAIR

ROBERT J. GORLIN 1 and BARNET M. LEVY 1

1 Columbia University, School of Dental and Oral Surgery of the Faculty of Medicine, New York, N. Y.

The changes in the mandibular joint and periodontium of vitamin B complex deficient rats were:

1. Diminution and cessation of chondrogenesis and osteogenesis.

2. Atrophy of connective tissues.

3. Serous atrophy of bone marrow.

4. Resorption of cementum and dentin.

Refeeding of stock diet resulted in:

1. Rapid resumption of chondrogenesis and osteogenesis.

2. Remodeling of bone.

3. Hyperplasia of fibrous connective tissue.

4. Repair of cementum and dentin by a cementum or bonelike substance.

Submitted on November 20, 1950







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