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J Dent Res 30(2): 182-188, 1951
© 1951 International and American Associations for Dental Research

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INVESTIGATIONS ON THE METABOLISM OF FLUORIDE

I. THE DETERMINATION OF FLUORIDE IN BLOOD

FRANK A. SMITH 1, DWIGHT E. GARDNER 1, M. J. VOSS 1, D. WING 1, P. DUNN 1, J. FIGUERAS 1, and J. W. KEATING 1

1 Division of Pharmacology and Toxicology, Department of Radiation Biology, School of Medicine and Dentistry, The University of Rochester, Rochester, N. Y.

1. The adaptation of standard methods of fluoride analysis to the determination of fluoride in blood is described. A statistical evaluation is made of the precision of the over-all method.

2. Values are given for the fluoride content of blood from several species of animals. The values for normal dogs and rabbits are comparable and, in most cases, are less than 10 µg of fluoride per 100 ml. of blood.

Submitted on April 28, 1950
Revised on January 20, 1951




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D. E. Gardner, F. A. Smith, H. C. Hodge, D. E. Overton, and R. Feltman
The Fluoride Content of Placental Tissue as Related to the Fluoride Content of Drinking Water
Science, February 22, 1952; 115(2982): 208 - 209.
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