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J Dent Res 29(6): 839-842, 1950
© 1950 International and American Associations for Dental Research

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THE EFFECT OF SINGLE DOSES OF IRRADIATION UPON THE ERUPTION OF THE UPPER RAT INCISOR

H. MEDAK 1, I. SCHOUR 1, and W. A. KLAUBER JR. 1

1 Department of Histology, College of Dentistry, and Department of Radiology, College of Medicine, University of Illinois, Chicago, Ill.

1. The rate of eruption of the upper incisors was measured in 84 albino rats ranging in age from 30 to 90 days following a single dose of x-ray irradiation, which was directed to the base of the upper incisors. The radiation dose ranged from 500 to 4000 r. in air. The rate of eruption was also measured in 12 normal white rats of similar age which were not exposed to irradiation.

2. The animals receiving 2000 and 2500 r. could be divided into 2 groups. One showed an increase, the other showed deceleration and cessation of eruption. Animals receiving 3000 and 4000 r. showed a depression in the rate of eruption within the first 2 weeks and then complete cessation.

3. Irradiation of the region of the hypophysis did not affect the rate of eruption.

Submitted on May 10, 1950







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