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1 Department of Pathology, College of Physicians and Surgeons, Columbia University, New York, N. Y.
The feeding of a purified diet containing 5 per cent glucoascorbic acid to weanling mice produced anorexia, mild alopecia, diarrhea, and weight loss. The histopathologic changes in the long bones and teeth were not compatible with the diagnosis of even initial scurvy. They resembled those changes ordinarily seen in inanition. The marrow of the bones and the pulp of the teeth as well as the viscera exhibited an increased vascularity.
Submitted on April 16, 1949
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