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1 School of Dental Medicine, and Department of Nutrition, School of Public Health, Harvard University, Boston, Mass.
The initiation and development of carious lesions in cotton rats was influenced by the type of cage and bedding in which they were housed during the experimental period. Cotton rats maintained in cages with screen floors had a significantly higher average number and a significantly higher average extent of carious lesions than littermates maintained throughout the experiment in cages with sheet metal floors covered with coarse wood shavings. Cotton rats, which were housed, in cages with sheet metal floors covered with paper clippings, did not have an appreciably different dental caries experience from their littermates in cages with screen floors.
Submitted on February 12, 1949
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