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J Dent Res 27(5): 547-552, 1948
© 1948 International and American Associations for Dental Research
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THE EFFECT OF HUMAN SALIVA ON THE CHOLERA VIBRIO IN VITRO:

A PILOT STUDY

CLARENCE E. DAWSON 1 and WILSON BLAGG 1

1 United States Naval Medical Research Unit No. 3, Cairo, Egypt

Saliva from normal healthy men was found to contain antibacterial activity against the cholera vibrio as demonstrated by its ability to inhibit growth and produce lysis of the cholera vibrio in vitro. This activity could not he demonstrated to the same degree in any of the cholera patients studied. The constancy of this agent varied in the same individual at different times. The active principle appeared to be a component of salivary secretion and to have the properties of an enzyme. The inhibitory potency of the saliva appeared to be associated with the state of health of the individual.

Submitted on April 7, 1948






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