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1 The Dight Institute of Human Heredity and the School of Dentistry, University of Minnesota, Minneapolis, Minn.
A brief report is made on the incidence of congenitally missing teeth in 3699 persons. The conditions observed in persons lacking second premolars are discussed.
Among 153 persons with congenitally missing second premolars, 330 of the premolars failed to develop. In these persons, 115 deciduous second molars were present at the time of examination.
Deciduous teeth were present or ample space still remained in 1 or more quadrants of 96 of the 153 persons who lacked second premolars. Of the others, 36 had no space and 21 had only slight space between the first premolar and first molar.
It is concluded that lack of space in the arches cannot account for the congenital loss of second premolars. It is suggested that the factor causing the loss of these teeth probably controls the development of the dental buds, and that the same factor effects the loss of the other kinds of teeth which are frequently missing.
Submitted on August 17, 1945
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