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J Dent Res 23(3): 155-162, 1944
© 1944 International and American Associations for Dental Research
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THE EFFECT ON CARIES INCIDENCE OF A SINGLE TOPICAL APPLICATION OF A FLUORIDE SOLUTION TO THE TEETH OF YOUNG ADULT MALES OF A MILITARY POPULATION

FRANCIS A. ARNOLD JR. 1, H. TRENDLEY DEAN 1, and DENNIS E. SINGLETON JR. 1

1 Dental Research Section, Division of Physiology, National Institute of Health, Bethesda, Md.

The results of a study in which a single topical application of fluoride was made to the teeth of Cadets at the U. S. Coast Guard Academy are reported:

1. After a complete dental examination, including radiographs and L. acidophilus counts, the Cadets were divided into 2 groups on a "matched pair" basis. Each member of one group had a partner in the other group who had a comparable oral condition in regard to the following: L. acidophilus count, fluoride exposure during the first 8 years of life, past caries experience, and age. Following a prophylaxis a sodium fluoride solution containing 5000 ppm. F, was applied to the teeth of one group (experimental) and a sodium chloride solution of equivalent concentration was applied to the teeth of the Cadets in the second group (controls). The period of observation was one year.

2. The observations made by the clinical examinations at the beginning and the end of the study period gave the following results: (a) The Cadets of the control and treated groups developed about the same number of new carious teeth, averaging 0.62 and 0.68 respectively. (b) The 2 groups showed similar gains in the number of new carious surfaces or areas as measured by Bodecker's index; controls averaged 2.2, experimental averaged 2.3.

3. Bacteriological examinations made on the saliva at 4 different times during the study year gave no indication of any change in the distribution of high and low L. acidophilus counts occurring in either of the groups.

4. There is no evidence in this study that a single topical application of a fluoride solution to the teeth of young adults as here carried out would result in reduction of dental caries incidence.

Submitted on April 4, 1944




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C. A. Schlack and J. E. Birren
Influences on Dental Defects in Naval Personnel
Science, September 20, 1946; 104(2699): 259 - 263.
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