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J Dent Res 23(1): 31-37, 1944
© 1944 International and American Associations for Dental Research
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THE EFFECT OF SYNTHETIC VITAMIN K AND RELATED COMPOUNDS ON THE RATE OF ACID FORMATION IN SALIVA

J. C. CALANDRA 1, O. E. FANCHER 1, and L. S. FOSDICK 1

1 Chemistry Department, Northwestern University Dental School, Chicago, Ill.

The effect of certain quinones and derivatives, and certain other compounds which may affect the oxidation reduction systems involved in the formation of acids by fermentation, have been tested for their effect on acid production in saliva. Of those tested, 2-methyl-1,4-naphthoquinone was found equal to any others tested, and superior to most of them. Aside from the quinones and derivatives, the only other compounds tested which were particularly effective were the various peroxides.

Submitted on December 8, 1943






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