THE EFFECT OF VITAMINS ON ACID FORMATION IN SALIVA
O. E. FANCHER 1,
J. C. CALANDRA 1, and
L. S. FOSDICK 1
1 Chemistry Department, Northwestern University Dental School, Chicago, Ill.
The effect of most of the known vitamins on acid formation from fermentable sugars in saliva has been studied. Only cholesterol, "Cerophyl", a mixture of vitamins, and possibly thiamin stimulated acid formation. Synthetic vitamin K (2-methyl-1,4-naphthoquinone) and natural vitamin K1 (2-methyl-3-phythl-1,4-naphthoquinone) inhibited acid formation. There was no indication that this action has any relationship to its vitamin K activity.
Submitted on December 8, 1943
