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J Dent Res 21(5): 437-442, 1942
© 1942 International and American Associations for Dental Research

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FAILURE TO PRODUCE DENTAL CARIES BY DISTURBING ACID-BASE BALANCE

BERNERD O. A. THOMAS D.D.S., M.S.1 and CHARLES F. BODECKER D.D.S.1

1 Laboratory of Oral Histology, Columbia University School of Dental and Oral Surgery, New York, N. Y.

Daily subcutaneous injections of NaHCO3 (6 animals), or alternate daily injections of NaHCO3 and NH4Cl (9 animals) failed to produce dental caries in albino rats. Histologic examination of the rats' teeth showed occasional abnormalities of the enamel matrix, ameloblasts, and odontoblasts. It was not possible to associate any of these conditions with the injection of either of the solutions used in the experiment.

Submitted on March 31, 1942







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