THE SECRETION OF INTRAVENOUSLY INJECTED FLUORINE IN THE SUBMAXILLARY SALIVA OF CATS

¹ Department of Physiology, University of Rochester School of Medicine and Dentistry, Rochester, N. Y.

When radioactive fluorine was injected intravenously into cats during secretion by the submaxillary gland, the injected material appeared in the saliva in significant amount within 1 minute after its administration. Under such conditions an average of 0.082 per cent of the fluorine entered the saliva during the 21 minutes following the injection. In similar experiments with radioactive chlorine 0.365 percent of the injected material was excreted in the saliva within 23 minutes.

When fluorine was injected into resting cats, the submaxillary gland not being stimulated until 50 minutes later, an average of 0.020 per cent of the fluorine was excreted in the saliva during the 21 minutes following the commencement of stimulation.

The ratio of saliva fluorine to plasma fluorine had an average value of 0.098; the similar ratio for chlorine was 0.389.