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1 Department of Pathology, School of Medicine and Dentistry, University of Rochester, Rochester, New York
1. High fevers occurring in rats affect the development of the dentin by producing concentric double-ringed zones, which follow the developmental lines of the teeth. The outer zone is probably hypocalcified and the inner portion hypercalcified.
2. Pulpal changes take the form of edema, hyperemia, a possible early reticular degeneration, and irregularity and thickening of the odontoblastic layer, from which the pulp recovers almost completely within 2 or 3 weeks.
3. The width of dentin change is in proportion to the duration of the fever.
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