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J Dent Res 19(1): 87-92, 1940
© 1940 International and American Associations for Dental Research

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THE TOXICITY AND RUBEFACIENT ACTION OF SULPHATED HIGHER ALCOHOLS

E. H. HATTON 1, L. S. FOSDICK 1, and J. CALANDRA 1

1 Departments of Pathology and Chemistry, Northwestern University Dental School, Chicago, Ill.

The continued ingestion of large amounts of sodium lauryl sulphate causes degenerative changes in the liver and intestinal mucosa of rats, but the amounts used were very greatly in excess of that found in tooth pastes and powders. The degree of surface irritation of human mucous membranes caused by this preparation is less than that of castile soap in the concentrations in which it is generally used. (Soap 5 to 16 percent; Irium, 1.25 percent.)




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Arch Intern MedHome page
S. J. FOGELSON and D. E. SHOCH
TREATMENT OF GASTRODUODENAL ULCERATIVE DISEASE WITH SODIUM ALKYL SULFATE: A PRELIMINARY REPORT
Arch Intern Med, March 1, 1944; 73(3): 212 - 216.
[Abstract] [PDF]




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