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J Dent Res 17(6): 493-498, 1938
© 1938 International and American Associations for Dental Research
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THE EFFECT OF SALIVA ON LACTOBACILLUS ACIDOPHILUS

OLIVER W. CLOUGH D.D.S., M.S.1, BASIL G. BIBBY B.D.S., PH.D.1, and GEORGE P. BERRY M.D.1

1 Department of Bacteriology, The University of Rochester, School of Medicine and Dentistry, Rochester, New York

Zones free of bacterial growth were produced in agar plates of Lactobacillus acidophilus about wells containing 250 of 260 salivas tested. These zones were shown to be manifestations of a bactericidal effect of the saliva. The active principle appeared to be a component of the salivary secretion. It was destroyed in 5 minutes at 75°C. Ultraviolet radiation and repeated freezings and thawings also inactivated it. The inhibitory potency of the saliva could not be correlated with the state of oral health in the individual from whom it was secured.






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