DENTAL OBSERVATIONS IN GAUCHER'S DISEASE

¹ Philadelphia, Pa.

1—Two cases of Gaucher's disease with lesions in the mandible and maxilla are described. 2—In the first case, the disease was recognized by intra-oral films. 3—In the second asymptomatic case, the dental roentgenographic findings aided the establishment of a tentative diagnosis of Gaucher's disease. 4—The presence of Gaucher's cells in the bone cortex and periosteum is reported for the first time. 5—Normal areas of rarefaction of the mandible differ from pathologic in that the pathologic, both sides are not uniform. 6—Generalized porosity in the mental region, pseudo-cystic areas of radiolucence in the molar and premolar mandibular region and presence of bone lysis in the maxillary premolar areas, are the three constant findings in the above two cases. 7—Bleeding from the gingiva is only present when there is an associated thrombocytopenia. 8—The dental findings in the above two cases may have some diagnostic significance.