STUDIES ON THE CHEMISTRY OF MIXED HUMAN SALIVA
III. THE COMPOSITION OF SALIVA PRODUCED AT VARYING RATES OF SECRETION BY THE SAME PERSON WITH SPECIAL REFERENCE TO CALCIUM AND PHOSPHORUS
J. B. BROWN PH.D.1,
H. D. WRIGHT B.Pharm., M.D.1, and
H. P. LIMBACHER B.S., M.D.1
1 Laboratory of Physiological Chemistry, Ohio State University, Columbus, Ohio
(1) In 1 subject specimens of saliva were produced over 5 one hour periods, the specimens in each case being taken at 15 minute intervals and subjected to analysis. During the 1 hour periods there was a tendency for calcium to decline and for phosphorus to be variable but the P/Ca values showed some tendency to increase due to fall of the calcium values. (2) Another subject produced 34 one hour specimens under a wide variety of chewing stimuli. The rate of secretion varied from 28 to 213 cc. per hour. When arranged according to rate of production, the specimens fall naturally into 3 groups—low, medium and high; the average composition of these groups may be correlated with rate of production very like the results previously reported for groups of individuals. (3) One subject chewed continuously for 6 hours. The regular fall in production rate was accompanied by decline in solids, ash and chloride. Phosphorus rose, then fell. Calcium nearly doubled in three of the specimens, concentration approaching that of blood serum.
