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J Dent Res 16(6): 545-550, 1937
© 1937 International and American Associations for Dental Research
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INHIBITION IN VITRO OF DECALCIFICATION IN TEETH

T. W. B. OSBORN 1, J. N. NORISKIN 1, and J. STAZ 1

1 Department of Physiology, University of the Witwatersrand, Johannesburg, S. Africa

1. By incubation in media containing refined sugar or cereals mixed with saliva decalcification was produced in healthy teeth. Calcium acid phosphate added to the incubating mixtures gave very little if any protection. 2. A mixture of calcium lactate and sodium glycerophosphate added to these decalcifying mixtures produced a marked reduction in the number of teeth attacked. 3. Calcium glycerophosphate was even more effective as a protective agent. 4. In none of the tubes was the pH significantly different from the controls; therefore these protective substances, like the "protective agent" postulated for crude cane juice and cereals, do not exert their effect by controlling pH.




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F. J. McClure
Cariostatic Effect of Phosphates
Science, June 12, 1964; 144(3624): 1337 - 1338.
[Abstract] [PDF]


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