Figure 2. Effects of IL-1ß, TNF-, and IL-17 (all 10 ng/mL for 48 hrs) on induction of proMMP-1 and MMP-3 concentration in gingival fibroblast cultures (n = 5) in vitro. proMMP-1 and especially MMP-3 were induced as a result of IL-1ß, TNF-, and IL-17 stimulation. The results are from triplicate measurements; mean ± SEM are shown. *p < 0.05, **p < 0.01, ***p < 0.001 (analyses by ANOVA).