Figure 3. Photomicrographs of tooth germs derived from mice on embryonic day 17 and cultured for 14 days. (a) Tooth germs cultured without oligo-deoxynucleotide. (b) Higher magnification of the boxed area in (a). (c) Tooth germs cultured with sense oligo-deoxynucleotide for the Phex. (d) Higher magnification of the boxed area in (c). (e) Tooth germs cultured with antisense oligo-deoxynucleotide for the Phex gene. (f) Higher magnification of the boxed area in (e). AB, ameloblasts; D, dentin; DP, dental papilla; EO, enamel organ; OB, odontoblasts.