Figure 3. The temporal pattern of the expression of Runx2 (A, n = 10), type X collagen (B, n = 10), BrdU-labeled cells in the erosive zone (C, n = 5), and the amount of new bone formation (D, n = 10) in the mandibular condyle during natural growth (Cont.) and during mandibular advancement (Exp.). Values were mean ± SD. Significant difference between control and experimental animals was marked with asterisks (*p < 0.05, **p < 0.01, ***p < 0.001).