Figure 2. High magnification showed the expression of Runx2 (A and D, in situ hybridization, arrows; B and E, immunohistochemical staining, arrowheads) and type X collagen (C and F: immunohistochemical staining) in the rat’s condylar cartilage during natural growth (A,B,C: 56 days old) and during mandibular advancement (D,E,F: 21 days after the experiment).