Figure 3. IL-1ß and VCAM-1 in pericoronitis (A,B, respectively) and healthy tissues (C,D, respectively). In pericoronitis (A), IL-1ß was found in fibroblast - and macrophage-like, vascular endothelial, and epithelial cells. (B) VCAM-1 was mainly localized in endothelial cells of the subepithelial blood vessels. In healthy controls (C), most of the IL-1ß-positive cells were vascular endothelial cells. Very few and weakly IL-1ß-positive subepithelial cells were observed in healthy controls. (D) VCAM-1 was rare. Scale bar = 200 µm; inserts were twice-magnified.