Figure 2. TNF- and its receptors in healthy control samples. (A) TNF- is almost exclusively localized in fibroblast-like cells and vascular endothelial cells. (B) TNF-R1 in a serial section is localized in stromal fibroblast-like cells and vascular endothelial cells. (C,D) Larger magnifications from the same samples but from different areas, showing TNF- and TNF-R1 staining, respectively. (E) In a serial section, weak TNF-R2 staining was occasionally found in a few stromal fibroblast- and macrophage-like, vascular endothelial, and basal epithelial cells. Scale bar = 200 µm.