Figure 1. Tumor necrosis factor- (TNF-) and its receptors in pericoronitis. (A) TNF- is localized in basal and suprabasal cells, basement membrane, monocyte/macrophage-, fibroblast-like, and vascular endothelial cells. Upper and lower inserts: Twice-magnified images of TNF--positive cells in the lamina propria. (B) No staining was detected in the negative control. (C) TNF-R1 in serial tissue sections is localized in monocyte/macrophage- and fibroblast-like cells, and vascular endothelial and basal epithelial cells. Upper and lower inserts: Twice-magnified images of TNF-R1-positive cells in the lamina propria. (D) TNF-R2 in a serial section is localized in monocyte/macrophage-and fibroblast-like cells, and vascular endothelial and basal epithelial cells. Upper and lower inserts: Twice-magnified images of TNF-R2-positive cells in the lamina propria. Scale bar = 200 µm.