Figure 3. Gingivomucosal section from non-ligature-treated rats (A) demonstrating no tissue damage. Inflammatory cell infiltration and edema were observed in gingivomucosal sections from ligature-treated rats (B). Significantly less edema and inflammatory cell infiltration were observed in gingivomucosal sections from ligature-treated rats which had been treated with aminoguanidine (100 mg/kg i.p., daily for 8 days) (C). Original magnification, x125. Fig. is representative of at least 3 experiments performed on different experimental days.