Figure 1. Inducible nitric oxide synthase (A) and myeloperoxidase activity (B), malondialdehyde levels (C), and Evans blue content (D) in gingivomucosal tissue was significantly increased by ligature compared with the contralateral side. Aminoguanidine (100 mg/kg i.p., daily for 8 days) significantly reduced inducible nitric oxide synthase and myeloperoxidase activity, malondialdehyde levels, and Evans blue content. Data are means ± SEM of n = 10 rats for each group. * P < 0.01 vs. non-ligated. P < 0.01 vs. ligated.