Figure 1. (A) Western immunoblot pattern demonstrating the cross-recognition of P. gingivalis HSP60 and human HSP60 by sera obtained from six atherosclerosis patients (A1-A6). This was not observed in healthy control subjects (N1-N6). Pairs of two lanes represent serum reactivity of one subject, left panels being against P. gingivalis HSP 60 (P), right panels being against human HSP 60 (H), respectively. (B) In addition, mouse anti-P. gingivalis HSP60 antisera recognized P. gingivalis HSP and cross-reacted with all the HSPs induced by heat-shock treatment of putative periodontopathogenic bacteria tested. Pg, P. gingivalis; Aa, A. actinomycetemcomitans; Bf, B. forsythus; Fn, F. nucleatum; Pi, P. intermedia; Td, T. denticola.