Figure 4. Photomicrographs showing VR1-immunoreactivity in the palatal intermolar rugae. Note the intense labeling in the summit of the rugal epithelium, where there are no VR1 nerves (A,B). The rich nerve supply with PGP (C) or CGRP (D) immunoreactivity to the rugae in a serial section of A. Elimination of staining with antibody pre-adsorbed with antigenic peptide (E). Scale bars: 50 µm.