Figure 3. CaEDTA attenuated zinc (Zn) toxicity, but not tin (Sn), copper (Cu), or silver (Ag) toxicity. Zn, ZnCl2; Sn, SnCl2; Cu, CuCl2; Ag, AgNO3; CaEDTA, 1 mM calcium disodium ethylenediaminetetraacetate. Bars show % cell death (mean + SEM, n = 6-16) quantified by the measurement of LDH release (A,B,C) or trypan blue staining (D), 24 hrs after the beginning of the insult. Sham wash values were subtracted, and results were scaled to the level measured in sister cultures exposed to 10 µM A23187 for 24 hrs. * indicates significant difference from the control metal toxicity.