Figure 1. Immunohistochemical staining of the premaxillary bone in 30-day-old mice with experimental tooth movement for 10 days. Many osteoblasts were detected on the tension side in the PDL space. VEGF in the osteoblasts was positively stained with VEGF-specific antibodies (A). No immunoreactivity was detected in the negative controls (B). Arrows indicate osteoblasts. PMB, premaxillary bone; MR, mesial side of the root.