Figure 4. The effect of genetic PARP deficiency on vascular permeability of gingivomucosal tissue (upper panel) and on alveolar bone destruction at the distal root (lower panel) in ligature-induced periodontitis in mice. Data are mean + SEM; n = 8 in both groups. a, significantly different (p < 0.05) from the contralateral side (non-ligated right side); b, significantly different (p < 0.05) from control (wild-type).