Figure 3. Immunolocalization of CNRs in rat incisor (red). (A) A monoclonal antibody that reacts with all CNR isoforms was used. The bulbous portion of the odontogenic epithelium and mesenchyme (a), secretory stage (b), early-maturation stage (c), and late-maturation stage of ameloblasts (d). Magnification: x40. (B) High magnification of the early-maturation stage of ameloblasts and odontoblasts (a); second antibody only (b). Magnification: x200. am, ameloblasts; pc, papillary cell layer; od, odontoblasts; de, dentin. Scale bars: 50 µm (Ad); 20 µm (Bb).