Figure 1. Nucleotide and inferred amino acid sequences of the fxp operon and of part of the contiguous genes from Streptococcus mutans 123.1 (accession #AF395874). Translation initiation sites of the open reading frames are shown. The -10 and -35 promoter regions are indicated by double underlining, and converging arrows illustrate transcriptional terminators. The CRE site and the direct repeat are shown by lightly shaded boxes. The protein regions corresponding to the DeoR family signature of FxpA, the PfkB family of carbohydrate kinases signatures of FxpB, and the IIC^Fru signature of FxpC are shadowed in black. The phosphorylated residues of the IIA and IIB domains of FxpC are boxed in gray. The putative substrate interacting sequence of FxpC is shadowed in gray.